For about 90 percent of men with prostate cancer, the cancer remains localized to the primary site, resulting in a five-year survival rate of almost 100 percent. Unfortunately, the remaining 10 percent of patients develop locally invasive and metastatic disease, which increases the severity of the disease and likelihood of death and limits treatment options. A report in The American Journal of Pathology indicates that a significantly lower presence of syntaphilin (SNPH)—a mitochondrial protein—within the tumor's central core versus at the tumor's invasive outer edge, may identify patients at increased risk of metastasis. These patients may require more rigorous testing, surveillance, and treatment.
* This article was originally published here
